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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
29.39
Human Site:
S2060
Identified Species:
49.74
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
S2060
S
V
A
M
A
D
D
S
L
W
K
P
L
N
Y
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
S2060
S
V
A
M
A
D
D
S
L
W
K
P
L
N
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
S2057
S
V
A
V
A
D
D
S
L
W
K
P
L
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
S2059
S
V
A
M
A
D
D
S
M
W
K
P
L
N
Y
Rat
Rattus norvegicus
NP_001101888
2143
241191
S2059
S
V
A
M
A
D
D
S
M
W
K
P
L
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
S2071
S
V
A
M
A
D
D
S
L
W
K
P
L
N
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
S2075
A
V
A
M
R
D
D
S
Q
W
K
V
L
N
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
V2012
F
A
V
A
T
N
D
V
M
W
K
Q
L
N
S
Honey Bee
Apis mellifera
XP_393800
2028
231830
S1944
A
S
A
I
P
D
D
S
L
H
K
Q
L
V
Y
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
L1574
E
L
L
N
K
I
M
L
K
T
R
D
S
R
A
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
L1559
K
F
T
S
V
G
F
L
S
Q
L
L
T
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
L1917
A
V
A
S
G
S
D
L
L
W
K
P
L
N
H
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
E1693
I
L
N
K
L
I
V
E
H
M
K
A
S
C
S
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
L1712
H
K
E
I
N
S
A
L
L
K
H
L
R
S
E
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
100
N.A.
73.3
N.A.
33.3
53.3
0
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
N.A.
80
N.A.
46.6
66.6
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
60
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
8
65
8
43
0
8
0
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
58
72
0
0
0
0
8
0
0
8
% D
% Glu:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% E
% Phe:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
8
8
8
0
0
0
8
% H
% Ile:
8
0
0
15
0
15
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
0
8
8
0
0
0
8
8
79
0
0
0
0
% K
% Leu:
0
15
8
0
8
0
0
29
50
0
8
15
72
0
0
% L
% Met:
0
0
0
43
0
0
8
0
22
8
0
0
0
0
0
% M
% Asn:
0
0
8
8
8
8
0
0
0
0
0
0
0
65
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
50
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
8
0
15
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
8
0
8
8
0
% R
% Ser:
43
8
0
15
0
15
0
58
8
0
0
0
15
15
15
% S
% Thr:
0
0
8
0
8
0
0
0
0
8
0
0
8
0
0
% T
% Val:
0
58
8
8
8
0
8
8
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
65
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
58
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _